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Niacinamide 100 PPM and 1000 PPM are used in cosmetics and personal care

Different Grades of Niacinamide 100 PPM and 1000 PPM and its use in cosmetics and personal care

What is Niacinamide?

Niacinamide is a water-soluble vitamin and is part of the vitamin B group. Also referred to as Vitamin B3 or Nicotinamide, it is well recognized as an essential nutrient when it comes to a well-functioning and healthy body. Niacinamide is a key component of the vitamin B complex, which includes other important vitamins such as thiamine (B1), riboflavin (B2), pantothenic acid (B5), pyridoxine (B6), biotin (B7), folate (B9), and cobalamin (B12).

History of Niacinamide: The Origin of Niacinamide- Unveiling the Story Behind an Amazing Star Ingredient

Niacinamide or Vitamin B3 is intertwined with the broader discovery and understanding of the vitamin B complex and its essential role in human health.

  1. Early Observations and Discovery: In the late 18th and early 19th centuries, pellagra ravaged population in Europe, particularly those dependent on diets heavy in maize (corn) as their primary staple. In 1906, Joseph Goldberger, an American epidemiologist, conducted studies that suggested pellagra was linked to poor diet rather than an infectious agent.
  2. Isolation and Identification: In the 1930s and 1940s, researchers made significant strides in isolating and identifying the compounds responsible for preventing and treating pellagra.
  3. Therapeutic Applications: Niacinamide and niacin were recognized for their therapeutic potential in treating pellagra and related conditions. Supplementation with niacinamide-rich foods or niacinamide supplements became standard practice for preventing and treating niacin deficiency disorders. Niacinamide and niacin quickly gained recognition for their therapeutic potential in treating and preventing niacin deficiency disorders, including pellagra.
  4. Contemporary Research and Applications: Niacinamide has gained widespread popularity in the cosmetic and skincare industry due to its proven efficacy in improving skin texture, reducing inflammation, and minimizing the appearance of wrinkles and fine lines. It is a common ingredient in moisturizers, serums, and other skincare products.

The history of Niacinamide is a testament to the transformative power of scientific inquiry and discovery in improving human health and well-being.

Niacinamide mechanism of action on skincare?

Niacinamide is a component of NAD and NADP, essential coenzymes in ATP production, also having a central role in DNA repair and skin homeostasis.  Niacinamide has been shown to enhance the repair of DNA damage in human keratinocytes and in human skin. It also has the potential to prevent UV-induced immune suppression and reduce skin pigmentation in 3D skin models.

  • Enhancement of Lipid Production: Ceramides are critical for maintaining the skin barrier function, preventing water loss, and protecting against environmental irritants.
  • Immune Response Enhancement: Enhanced immune response helps the skin to better resist infections and recover more effectively from damage. Nicotinamide protects against UVA- and UVB-induced DNA damage in melanocytes, activating nucleotide excision repair genes and NRF2 signaling. These diverse actions make niacinamide a valuable component in skin care products for various skin conditions.

Also Read: Types of Silicones used in Personal Care & Cosmetics

Properties and Features of Niacinamide

Niacinamide stands out as a multifaceted nutrient with a plethora of properties and features that contribute to its diverse range of applications in skincare, health, and beyond.

  1. Anti-Inflammatory: It helps to reduce redness, swelling, and discomfort associated with various skin conditions, including acne, rosacea, and eczema.
  2. Moisturizing: The moisturizing effect helps to keep the skin soft, supple, and plump, reducing the appearance of fine lines, wrinkles, and dryness.
  3. Antioxidant: The niacinamide helps to prevent premature aging, sun damage, and other forms of skin damage, preserving the skin’s youthful appearance and vitality.
  4. Collagen Production: The niacinamide helps to improve skin texture and reduce the signs of aging, such as fine lines, wrinkles, and sagging skin.

From its anti-inflammatory and moisturizing properties to its antioxidant and brightening effects, niacinamide offers a multitude of benefits for improving skin health, texture, and appearance.

Unlocking the Benefits of Niacinamide

Niacinamide offers a multitude of benefits for both health and beauty. Whether you’re looking to improve skin health and appearance, support cardiovascular function, or enhance overall well-being, niacinamide has the versatility and efficacy to meet your needs. As a powerhouse ingredient in skincare and nutrition, niacinamide continues to captivate researchers, formulators, and consumers alike, unlocking a world of possibilities for optimizing health and beauty routines.

  1. Skin Health and Appearance: Niacinamide helps to regulate sebum production and tighten enlarged pores, resulting in a smoother and more refined skin texture. Niacinamide stimulates collagen production, improving skin firmness and elasticity while reducing the appearance of fine lines, wrinkles, and sagging skin.
  2. Overall Health and Well-Being: Niacinamide has been shown to have a modest effect on improving lipid profiles, lowering LDL cholesterol levels, and increasing HDL cholesterol levels, thus reducing the risk of cardiovascular disease. Niacinamide is essential for energy production in cells, aiding in the metabolism of carbohydrates, fats, and proteins.
  3. Compatibility and Versatility: Niacinamide is stable in various formulations and pH conditions, allowing it to be combined with other active ingredients, such as retinoids, vitamin C, and alpha hydroxy acids, for synergistic effects. It is non-irritating, non-comedogenic, and unlikely to cause allergic reactions, making it suitable for use in a wide range of skincare formulations.
  4. Minimizes enlarged pores: The Secret to Minimizing Enlarged Pores for Smoother Skin, Niacinamide helps to regulate sebum production by controlling the activity of sebaceous glands. By reducing excess oil, niacinamide helps to prevent pores from becoming clogged, which in turn makes them appear smaller and less noticeable.
  5. Improves Uneven Skin Tone and Hyperpigmentation: Niacinamide is highly effective in addressing hyperpigmentation and uneven skin tone. It works by inhibiting the transfer of melanin to the surface of the skin, which helps fade dark spots and discoloration.
  6. Provides Anti-Aging Benefits: Niacinamide offers significant anti-aging benefits by stimulating collagen production and improving skin elasticity.

Niacinamide offers a multitude of advantages that make it a standout ingredient in various products and formulations. Vitamin B3 is necessary to maintain energy and general vitality as it helps to release energy and nutrients from foods. Niacinamide & Niacin, both compounds are identical in their vitamin function.

Also Read: Synthetic Iron Oxide Suppliers and Manufacturers in India

Grades of Niacinamide 100 PPM and 1000 PPM

The grades of niacinamide typically refer to the concentration or purity of the compound in a solution. “PPM” stands for “parts per million,” A unit of concentration often used in chemistry to denote minimal amounts of a substance dissolved in another. Niacinamide with different Niacin content to suit customer needs. Niacinamide with less than 100 ppm Niacin and Niacinamide with less than 1000 ppm Niacin. Both grades have stringent Microbiology specifications, i.e., TVC < 100 CFU/gm and are free from undesirable pathogens in cosmetic formulations.

The primary difference between niacinamide 100 PPM and 1000 PPM lies in their concentration levels and corresponding efficacy. Niacinamide 100 PPM offers a gentle approach suitable for daily use and sensitive skin, while niacinamide 1000 PPM provides a more potent option for targeted treatments and quicker results.

Niacinamide 100 PPM is a Low Concentration for Gentle Applications: It is particularly suitable for products designed for sensitive skin. It is often used in products intended for daily use, such as moisturizers, toners, and serums, where gentle, long-term application can provide cumulative benefits without overwhelming the skin.

Niacinamide 1000 PPM is a Higher Concentration for Targeted Treatments: It is a higher concentration, making it more effective for targeted treatments addressing specific skin concerns such as acne, hyperpigmentation, and pronounced signs of aging. It is designed to provide intensive care and address particular issues like dark spots, wrinkles, and excessive oiliness.

Everyday Products vs. Treatment Products: Niacinamide 100 PPM is excellent for formulating everyday skincare products that provide gentle, ongoing benefits. Niacinamide 1000 PPM is better suited for treatment products aimed at providing intensive care and addressing specific skin concerns.

Niacinamide 100 PPM: Niacinamide 100 PPM denotes a meticulously measured concentration, with 100 parts of niacinamide meticulously blended into a million parts of the solution.

  1. Niacinamide 100 PPM concentration, niacinamide can be precisely incorporated into serums, creams, and treatments to deliver potent yet gentle skincare solutions.
  2. Niacinamide 100 PPM into skincare formulations, product efficacy is enhanced, ensuring that users experience noticeable improvements in their skin’s health and appearance.
  3. Niacinamide 100 PPM finds applications in various industries, including pharmaceuticals, food and beverage, and industrial processes.

Niacinamide is one of the most stable vitamins. It is freely water soluble and the solution is light stable. The optimum solution stability is at a pH of 4.5-6. It is very stable to most oxidizing and reducing agents.

Niacinamide 1000 PPM: Niacinamide 1000 PPM signifies a concentrated formulation, with 1000 parts of niacinamide blended into a million parts of the solution. Niacinamide was considered non-toxic at levels considerably higher than would be experienced in cosmetic products. Hence, considered safe in cosmetic formulations.

  1. Formulations containing Niacinamide 1000 PPM can effectively target stubborn skin issues and promote overall skin health and vitality.
  2. Formulated as serums, creams, or masks, products containing this concentration of niacinamide can deliver intensive care and noticeable results, making them suitable for addressing complex skin conditions and concerns.
  3. Its versatility and heightened potency make it a valuable ingredient for formulating medications, nutritional supplements, and additives with enhanced therapeutic benefits and efficacy.

Niacinamide (vitamin B3) is a very stable vitamin that offers a wide range of well-documented topical benefits. Niacinamide is a component of NAD and NADP, essential coenzymes in ATP production, also having a central role in DNA repair and skin homeostasis. Clinical testing of Niacinamide produced no stinging sensations at concentrations up to 10%, use tests produced no irritation at concentrations up to 5% and a 21-day cumulative irritation test at concentrations up to 5% resulted in no irritancy. Niacinamide was also neither a sensitizer nor a photosensitizer.

Also Read: Pigment Colors for Cosmetics and Personal Care Products

Niacinamide Applications in Personal Care

Niacinamide exhibits potent anti-inflammatory properties, making it an effective ingredient for soothing and calming irritated or sensitive skin.  As consumer demand for effective and science-backed skincare products continues to rise, niacinamide’s role in personal care is poised to expand further, cementing its status as a must-have ingredient in modern skincare routines.

Niacinamide (Nicotinamide) is a multifunctional, high-value-added, cost-effective, globally approved ingredient that should be considered for use in most skin care formulations. Its numerous skincare benefits have been extensively substantiated in numerous peer-reviewed scientific journals and publications. It has been used in dermatology for more than 45 years for a diverse range of conditions including acne, rosacea, psoriasis, autoimmune bullous dermatoses, the treatment and prevention of photoaging, and photoimmunosuppression.

Niacinamide Moisturizes Skin: Niacinamide possesses humectant properties, meaning it has the ability to attract and retain moisture from the environment and deeper layers of the skin.  White petrolatum is the standard against which other moisturizers are compared, because of its hydrating properties. Nicotinamide significantly decreased transepidermal water loss, but white petrolatum did not show any significant effect. Both Nicotinamide and white petrolatum increased stratum corneum hydration, but Nicotinamide was significantly more effective than white petrolatum.

Niacinamide an Effective Anti-aging Agent: As a powerhouse ingredient in skincare, niacinamide has garnered acclaim for its ability to combat signs of aging effectively. 5% topical Niacinamide Reduces Yellowing, Wrinkling, Red Blotchiness, and Hyper-pigmented Spots in Aging Facial Skin. Niacinamide acts as an effective antioxidant, neutralizing free radicals generated by UV exposure and protecting the skin from oxidative stress. By shielding the skin against UV damage, niacinamide helps to prevent the breakdown of collagen and elastin fibers, preserving skin elasticity and preventing premature aging.

Niacinamide Helps in Skin Lightening: Niacinamide reduces dark skin discoloration with lesser side effects than Hydroquinone.  Niacinamide reinforces the skin barrier, enhancing its resilience and integrity. Its non-irritating and non-sensitizing nature makes it suitable for all skin types, including sensitive and acne-prone skin. Overproduction or uneven distribution of melanin can lead to hyperpigmentation and dark spots, disrupting the skin’s natural radiance.

Niacinamide Reduces Skin Oiliness: Niacinamide helps to regulate sebum production by inhibiting the activity of sebaceous glands, which are responsible for producing oil. Oily skin can still be dehydrated, leading to an overcompensation of oil production as the skin attempts to moisturize itself. The presence of sebum on the face is responsible for both facial shine and the formation of inflammatory acne lesions. Topical 2% Niacinamide may be effective in lowering the sebum excretion rate (SER) in Japanese individuals and Casual sebum level (CSL) in Caucasian individuals. A formulation containing 2% Niacinamide was shown to reduce sebum by 30% and pore size by 10% after 4 weeks of use (P&G US patent 583998-11/98). Niacinamide’s anti-inflammatory and antibacterial properties help to combat acne by reducing inflammation and inhibiting the growth of acne-causing bacteria. By improving makeup wear, niacinamide allows for a more long-lasting and flawless makeup look.

Bansal Trading Company is a dominant global Niacinamide Chemical Distributors and Supplier

Bansal Trading Company has earned a reputation for excellence, particularly in the distribution of niacinamide chemicals. The company 75 Years of sustainable growth. A legacy is unparalleled not just because of the pioneering status and experience, but the dedication of four generations resulting in time-tested relationships both with our customers and principals.  Bansal Trading Company is a market leader in most of its product lines. We don’t get into alliances just to add a marquee name to our portfolio. Our alliances go through the comprehensive evaluation process and product lines are added only if we can be a part of our partners’ growth story. Resulting in a leadership position in most of the product lines we have the pleasure of marketing.

Conclusion: Bansal Trading Company stands as a dominant force in the global chemical distribution landscape, specializing in the supply of premium-grade niacinamide 100 PPM and 1000 PPM. Bansal Trading Company upholds stringent quality standards to deliver niacinamide 100 PPM and 1000 PPM chemicals of the highest purity and efficacy.


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